Subha Mukherji, on behalf of the Crossroads of Knowledge project, has won a Cambridge Humanities Research Grant to supplement the project’s qualitative research with quantitative computational analysis. This has been used to set up a new collaboration with the Humanities Digital Workshop at the George Washington University, St Louis, to work on a pilot study, Computational Mapping: Crossroads of Knowledge, from July to September 2017. Dr Michael Witmore and Professor Jonathan Hope, both project Advisors, have overseen and helped set up the collaboration. Professor Anupam Basu and Dr Lauren Kersey will be Visiting Fellows this summer, helping the team apply digital tracking to their material with a view to charting a grammar and syntax of knowing, as well as asking chronological questions about semantic and conceptual shifts in key early modern ideas. This innovative pilot study should offer a new model in the uses of technology in interdisciplinary humanities.